Strain Data Sheet

RBRC00062

Strain Information

Image
BRC No.RBRC00062
TypeCongenic
SpeciesMus musculus
Strain nameC.B6-Enpp1<b>/Rbrc
Former Common nameBALB-PC(-), BALB-Enpp1<b>
H-2 Haplotype
ES Cell line
Background strainBALB/cA
Appearancealbino [A/A b/b c/c]
Strain developmentDeveloped by Toshitada Takahashi, Aichi Cancer Center Research Institute.
Strain descriptionPC-1 congenic strain. BALB/c background strain (RBRC00062) having negative typed plasma cell antigen (PC-1 negative, Enpp1<b>) from C57BL/6. C57BL/6 background strain (RBRC00128) having positive type plasma cell antigen (PC-1 positive, Enpp1<a>) from BALB/c.
Colony maintenanceHomozygote x Homozygote
References
Surface alloantigens of plasma cells.
Takahashi T, Old L J, Boyse E A
J. Exp. Med., 131, 1325 (1970). 5419273

Structural basis of allotypes of ecto-nucleotide pyrophosphatase/phosphodiesterase (plasma cell membrane glycoprotein PC-1) in the mouse and rat, and analysis of allele-specific xenogeneic antibodies.
Banakh I, Sali A, Dubljevic V, Grobben B, Slegers H, Goding J W
Eur. J. Immunogenet., 29, 307-313 (2002). 12121276

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Enpp1
MGI:97370		ectonucleotide pyrophosphatase/phosphodiesterase 110Enpp1<b> b variant
  • arterial calcification, generalized, of infancy, 1(MedGEN)

  • hypophosphatemic rickets, autosomal recessive, 2(MedGEN)

  • hypopigmentation-punctate palmoplantar keratoderma syndrome(MedGEN)
    • more 2 Diseases
  • obesity disorder(MedGEN)

  • type 2 diabetes mellitus(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationImmunology and Inflammation Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorToshitada Takahashi (Aichi Cancer Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data