Strain Data Sheet

RBRC00197

Strain Information

Image
BRC No.RBRC00197
TypeInbred
SpeciesMus musculus
Strain nameIITES
Former Common nameII-TES
H-2 Haplotype
ES Cell line
Background strainIITES
Appearancedilute brown, piebald [a/a b/b C/C d/d P/P s/s]
Strain developmentDeveloped by Dr. Kyoji Kondo at Nagoya University, School of Agriculture. Originally mixed background of CS, DBA/2, NC and ITES strains.
Strain descriptionThese mice have 4 autosomal recessive coat color genes (a/a b/b d/d s/s) and are useful for testing color genes.
Colony maintenanceSibling Mating (Homozygote x Homozygote)
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Ednrbendothelin receptor type B14Ednrbpiebald
  • ABCD syndrome(MedGEN)

  • Griscelli syndrome type 1(DisGeNET, MedGEN)

  • Hirschsprung disease, susceptibility to, 2(MedGEN)
  • more 3 Diseases
  • oculocutaneous albinism type 2(DisGeNET, MedGEN)

  • oculocutaneous albinism type 3(MedGEN)

  • Waardenburg syndrome type 4A(MedGEN)
  • anonagouti2anonagouti
  • ABCD syndrome(MedGEN)

  • Griscelli syndrome type 1(DisGeNET, MedGEN)

  • Hirschsprung disease, susceptibility to, 2(MedGEN)
  • more 3 Diseases
  • oculocutaneous albinism type 2(DisGeNET, MedGEN)

  • oculocutaneous albinism type 3(MedGEN)

  • Waardenburg syndrome type 4A(MedGEN)
  • Tyrp1tyrosinase-related protein 14Tyrp1brown
  • ABCD syndrome(MedGEN)

  • Griscelli syndrome type 1(DisGeNET, MedGEN)

  • Hirschsprung disease, susceptibility to, 2(MedGEN)
  • more 3 Diseases
  • oculocutaneous albinism type 2(DisGeNET, MedGEN)

  • oculocutaneous albinism type 3(MedGEN)

  • Waardenburg syndrome type 4A(MedGEN)
  • Oca2oculocutaneous albinism II7Oca2

    pink-eyed dilution
  • ABCD syndrome(MedGEN)

  • Griscelli syndrome type 1(DisGeNET, MedGEN)

  • Hirschsprung disease, susceptibility to, 2(MedGEN)
  • more 3 Diseases
  • oculocutaneous albinism type 2(DisGeNET, MedGEN)

  • oculocutaneous albinism type 3(MedGEN)

  • Waardenburg syndrome type 4A(MedGEN)
  • Myo5amyosin VA9Myo5adilute
  • ABCD syndrome(MedGEN)

  • Griscelli syndrome type 1(DisGeNET, MedGEN)

  • Hirschsprung disease, susceptibility to, 2(MedGEN)
  • more 3 Diseases
  • oculocutaneous albinism type 2(DisGeNET, MedGEN)

  • oculocutaneous albinism type 3(MedGEN)

  • Waardenburg syndrome type 4A(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • abnormal coat/hair pigmentation(MP:0002075)

  • abnormal dorsoventral coat patterning(MP:0008238)

  • abnormal foot pigmentation(MP:0009379)

  • abnormal hair shaft melanin granule distribution(MP:0008733)

  • abnormal hair shaft melanin granule morphology(MP:0008731)
  • more 14 phenotypes
  • abnormal iris morphology(MP:0001322)

  • abnormal melanocyte morphology(MP:0002877)

  • abnormal tail pigmentation(MP:0005174)

  • darkened coat color(MP:0005409)

  • decreased body size(MP:0001265)

  • decreased eye pigmentation(MP:0005172)

  • endocrine/exocrine gland phenotype(MP:0005379)

  • enlarged hair follicle melanin granules(MP:0005071)

  • iris atrophy(MP:0006228)

  • megacolon(MP:0002731)

  • reduced hair shaft melanin granule number(MP:0008732)

  • variable body spotting(MP:0002940)

  • variable depigmentation(MP:0010016)

  • white spotting(MP:0002938)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and Conditions
    DepositorMasahiko Nishimura (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    Osipova DV, Kulikov AV, Mekada K, Yoshiki A, Moshkin MP, Kotenkova EV, Popova NK.
    Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice.
    Genes Brain Behav 9(5) 537-43(2010) 20398061