Strain Data Sheet

RBRC00532

Strain Information

Image
BRC No.RBRC00532
TypeCongenic
SpeciesMus musculus
Strain nameC57BL/10SnSlc-H2<aw18>/H2<b>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Lethal deletion of the complement component C4 and steroid 21-hydroxylase genes in the mouse H-2 class III region, caused by meiotic recombination.
Shiroishi T, Sagai T, Natsuume-Sakai S, Moriwaki K
Proc. Natl. Acad. Sci. USA, 84, 2819-2823 (1987). 3495003

Health Report

Examination Date / Room / Rack2024/08/26Room:4-CRack:HSentinel mouse program
2024/05/27Room:4-CRack:HSentinel mouse program
2024/02/26Room:4-CRack:HSentinel mouse program
2023/11/27Room:4-CRack:HSentinel mouse program
2023/08/28Room:4-CRack:HSentinel mouse program
2023/05/29Room:4-CRack:HSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
H2
MGI:95894		histocompatibility-2, MHC17H2<b>
MGI:3579319		b variant
H2
MGI:95894		histocompatibility-2, MHC17H2<aw18> aw18 variant

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased physiological sensitivity to xenobiotic(MP:0008874)

  • decreased susceptibility to autoimmune diabetes(MP:0004804)

  • periinsulitis(MP:0005580)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. U S A, 84, 2819-2823 (1987). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorToshihiko Shiroishi (National Institute of Genetics)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-
    DDBJ: AY613781.1

    BRC mice in Publications

    No Data