Strain Data Sheet

RBRC00693

Strain Information

Image
BRC No.RBRC00693
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameAKR/J-Foxn1<nu-str>/StmRbrc
Former Common nameAKR/J-nu<str>
H-2 Haplotypek
ES Cell line
Background strain
Appearancealbino nude [nu]
albino
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Foxn1
MGI:102949
forkhead box N111Foxn1<nu-str>
MGI:1856109
nude streaker
  • T-cell immunodeficiency, congenital alopecia, and nail dystrophy(DisGeNET, MedGEN)

  • T-cell lymphopenia, infantile, with or without nail dystrophy, autosomal dominant(MedGEN)
  • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal Peyer's patch germinal center morphology (MP:0002391)

  • abnormal Peyer's patch morphology (MP:0000696)

  • abnormal humoral immune response (MP:0001800)

  • abnormal immune system cell morphology (MP:0000716)

  • abnormal immune system morphology (MP:0000685)
  • more 18 phenotypes
  • abnormal immune system organ morphology (MP:0002722)

  • abnormal immune system physiology (MP:0001790)

  • athymia (MP:0000705)

  • cachexia (MP:0005150)

  • decreased T cell number (MP:0005018)

  • decreased immunoglobulin level (MP:0002460)

  • decreased incidence of tumors by chemical induction (MP:0004502)

  • decreased lymphocyte cell number (MP:0005016)

  • decreased lymphoma incidence (MP:0010268)

  • hairless (MP:0003815)

  • increased eosinophil cell number (MP:0005011)

  • increased granulocyte number (MP:0000322)

  • increased length of allograft survival (MP:0004751)

  • increased neutrophil cell number (MP:0000219)

  • increased sarcoma incidence (MP:0002032)

  • lymph node hypoplasia (MP:0008101)

  • premature death (MP:0002083)

  • spleen hypoplasia (MP:0000694)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorHayase Shisa (Saitama Cancer Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data