Strain Data Sheet

RBRC01083

Strain Information

Image
BRC No.RBRC01083
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129S-Drd4<tm1Mok>
Former Common nameD4R KO, B6-D4R KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionD4R (Drd4) gene knockout mice. Homozygous mutant mice show no obvious abnormality.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Drd4
MGI:94926		dopamine receptor D47Drd4<tm1Mok>
MGI:6376626		targeted mutation 1, Motoya Katsuki
  • attention deficit-hyperactivity disorder(MedGEN)
    • Ecogpt E.coli xanthine phosphoribosyltransferase7Ecogpt mouse phosphoglycerate kinase promoter (PGK promoter)
    neo neomycin resistance gene (E. coli)7 mouse RNA polymerase II large subunit promoter

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse RNA polymerase II large subunit promoter, E coli neo, E. coli xanthine phosphoribosyltransferase(Ecogpt), mouse Drd4 genomic DNA
    Research applicationNeurobiology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 未定In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorToshikuni Sasaoka (Niigata University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data