Strain Data Sheet

RBRC01129

Strain Information

Image
BRC No.RBRC01129
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBLBRTF-Ttf/t<w5>tf/Rbrc
Former Common nametw5
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Itpr3
MGI:96624		inositol 1,4,5-triphosphate receptor 317Itpr3<tf>
MGI:1857070		tufted
  • type 1 diabetes mellitus(MedGEN)
    • T
    MGI:98472    		brachyury, T-box transcription factor T17T
    MGI:1856184    		brachyury
  • neural tube defect(MedGEN)

  • sacral agenesis-abnormal ossification of the vertebral bodies-persistent notochordal canal syndrome(MedGEN)
    • t
    MGI:105076    		t-complex17t<w5>
    MGI:1856570    		t, wild 5

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal allogrooming behavior (MP:0011000)

  • abnormal brain commissure morphology (MP:0002199)

  • abnormal cerebral cortex morphology (MP:0000788)

  • abnormal coat/ hair morphology (MP:0000367)

  • abnormal dorsal aorta morphology (MP:0004787)
    • more 48 phenotypes
  • abnormal epidermal layer morphology (MP:0001216)

  • abnormal forelimb bud morphology (MP:0013164)

  • abnormal gustatory system physiology (MP:0001985)

  • abnormal hair cycle (MP:0000427)

  • abnormal hair growth (MP:0002073)

  • abnormal head shape (MP:0011495)

  • abnormal heart looping (MP:0000269)

  • abnormal heart tube morphology (MP:0000270)

  • abnormal limb bud morphology (MP:0005650)

  • abnormal liquid preference (MP:0001423)

  • abnormal locomotor activation (MP:0003313)

  • abnormal neocortex morphology (MP:0008547)

  • abnormal nervous system development (MP:0003861)

  • abnormal neural tube morphology (MP:0002151)

  • abnormal notochord morphology (MP:0002825)

  • abnormal pericardial cavity morphology (MP:0012501)

  • abnormal placenta development (MP:0001712)

  • abnormal primitive streak formation (MP:0002230)

  • abnormal social investigation (MP:0001360)

  • abnormal somite development (MP:0001688)

  • abnormal vocalization (MP:0001529)

  • absent corpus callosum (MP:0002196)

  • absent hindlimb buds (MP:0013168)

  • absent notochord (MP:0000932)

  • bleb (MP:0008854)

  • caudal body truncation (MP:0004073)

  • decreased anterior commissure size (MP:0008226)

  • decreased anxiety-related response (MP:0001364)

  • decreased caudal vertebrae number (MP:0001539)

  • decreased embryo size (MP:0001698)

  • decreased hippocampal commissure size (MP:0008222)

  • decreased presacral vertebrae number (MP:0000461)

  • decreased ventral ectodermal ridge size (MP:0012714)

  • delayed heart development (MP:0012082)

  • embryonic lethality during organogenesis, complete penetrance (MP:0011098)

  • excessive vocalization (MP:0013140)

  • hemopericardium (MP:0005244)

  • hemorrhage (MP:0001914)

  • impaired social transmission of food preference (MP:0002969)

  • increased body weight (MP:0001260)

  • increased fluid intake (MP:0011941)

  • increased grooming behavior (MP:0001441)

  • increased growth rate (MP:0002865)

  • kinked neural tube (MP:0003400)

  • low sweet preference (MP:0012347)

  • notochord degeneration (MP:0004712)

  • short tail (MP:0000592)

  • sparse hair (MP:0000416)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization.
    The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research.
    In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation.
    The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution.
    DepositorHirokazu Fujimoto (Mitsubishi Kasei Institute of Life Sciences)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data