Strain Data Sheet

RBRC01365

Strain Information

Image
BRC No.RBRC01365
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameICR.Cg-Tg(CAG-cat,-Nkx2-5)13Ysa/YsaRbrc
Former Common nameCAG-CAT-Nkx2.5#13
H-2 Haplotype
ES Cell line
Background strainICR
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Nkx2-5
MGI:97350		NK2 homeobox 5UNNkx2-5
  • atrial septal defect 7(DisGeNET, MedGEN)

  • conotruncal heart malformations(MedGEN)

  • hypoplastic left heart syndrome 2(MedGEN)
    • more 4 Diseases
  • hypoplastic left heart syndrome(DisGeNET)

  • hypothyroidism, congenital, nongoitrous, 5(MedGEN)

  • tetralogy of fallot(DisGeNET, MedGEN)

  • ventricular septal defect 3(MedGEN)
    • cat E. coli chloramphenicol acetyltransferase (CAT)UN CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
    loxP phage P1 loxPUNloxP
    loxP phage P1 loxPUNloxP

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), E. coli chloramphenicol acetyltransferase (CAT) gene, poly A, Nkx2.5 cDNA, Phage P1 loxP
    Research applicationCre/loxP system
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Within a period of 2 years after deposition of the material, user must contact the DEPOSITOR and notify him a content of the research. If the DEPOSITOR judges that the research should be a collaborative work, then user must include DEPOSITOR and/or developer's names as co-authors.
    DepositorYumiko Saga (National Institute of Genetics)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. CAGGS MTA (English)
    5. Acceptance of responsibility for living modified organism (Japanese / English)
    Saga Lab HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data