Strain Information | |
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Image | ![]() |
BRC No. | RBRC01683 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | B6.Cg-Pcdha<tm(CP)>/TyagRbrc |
Former Common name | CNR CP |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University in 2005. TT2 ES cells were used to generate the knockout mice. |
Strain description | A polyA sequence in the CP exon of CNR (Pchda) was replaced with a neo cassette. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6J(Crlj)] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Pcdha MGI:3719085 | protocadherin alpha cluster | 18 | Pcdha<tm(CP)> | targeted mutation | |||
loxP | phage P1 loxP | 18 | loxP | ||||
loxP | phage P1 loxP | 18 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 18 | herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Phage P1 loxP, herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse Pcdha genomic DNA |
Research application | Cell Biology Research Cre/loxP system Neurobiology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR. |
Depositor | Takeshi Yagi (Osaka University) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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Nakata H, Hashimoto T, Seki Y, Mekada K, Obata Y, Yoshiki A. Simultaneous detection of multiple transgenes for genetically-modified mouse strains. Exp Anim 58(4) 437-42(2009) 19654444 |