Strain Information | |
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Image | ![]() |
BRC No. | RBRC02106 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | B6.129-Lefty1<tm1Hmd> |
Former Common name | lefty 1 null KO |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Meno C, Shimono A, Saijoh Y, Yashiro K, Mochida K, Ohishi S, Noji S, Kondoh H, Hamada H Cell, 94, 287-297 (1998). 9708731 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Lefty1 MGI:107405 | left right determination factor 1 | 1 | Lefty1<tm1Hmd> MGI:2179534 | targeted mutation 1, Hiroshi Hamada | |||
neo | neomycin resistance gene (E. coli) | 1 | SV40 and herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 19 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | SV40 初期遺伝子プロモーター, HSV チミジンキナーゼ遺伝子プロモーター, E. coli 由来ネオマイシン耐性遺伝子, SV40Ter 遺伝子のpolyA 付加シグナル |
Research application | Developmental Biology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 94, 287-297 (1998). |
Depositor | Hiroshi Hamada (RIKEN CDB) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Mouse of the Month May 2007 |
BRC mice in Publications |
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No Data |