Strain Data Sheet

RBRC02114

Strain Information

Image
BRC No.RBRC02114
TypeMajor Histocompatibility Complex (H2) Congenic
SpeciesMus musculus
Strain nameNOD.CTS-H2(D17Mit30-D17Mit104)
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.
Ikegami H, Makino S, Yamato E, Kawaguchi Y, Ueda H, Sakamoto T, Takekawa K, Ogihara T
J. Clin. Invest., 96, 1936-1942 (1995). 7560085

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
H2
MGI:95894		histocompatibility-2, MHC17H2

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • cataract(MP:0001304)

  • decreased lymphocyte cell number(MP:0005016)

  • increased susceptibility to autoimmune disorder(MP:0005350)

  • insulitis(MP:0004031)

  • polydipsia(MP:0001426)
    • more 2 phenotypes
  • polyuria(MP:0001762)

  • weight loss(MP:0001263)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationDiabetes and Obesity Research
    covid19_progression
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorHiroshi Ikegami (Osaka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data