Strain Data Sheet

RBRC02297

Strain Information

Image
BRC No.RBRC02297
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameKbus/Idr
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Dr. Satoshi Yonezawa, Institute for Developmental Research, Aichi Prefectural Colony in 2002. Originated from KYF/MsIdr.
Strain descriptionSpontaneous mutant strain exhibiting small body and shortened tail.
Colony maintenanceSibling Mating (Homozygote x Hemizygote)
References
Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: identification as an allele of 'Hyp'.
Moriyama K, Hanai A, Mekada K, Yoshiki A, Ogiwara K, Kimura A, Takahashi T
J. Biomed. Sci., 18(1):60 (2011). 21854633

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Phex
MGI:107489		phosphate regulating endopeptidase homolog, X-linkedXPhex<Kbus>
MGI:7262900		hypophosphatemia; Kbus
  • X-linked dominant hypophosphatemic rickets(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • abnormal bone marrow cell physiology(MP:0009278)

  • abnormal bony labyrinth(MP:0004289)

  • abnormal craniofacial bone morphology(MP:0002116)

  • decreased bone mineral density(MP:0000063)

  • decreased length of long bones(MP:0004686)
    • more 3 phenotypes
  • disproportionate dwarf(MP:0002427)

  • increased alkaline phosphatase activity(MP:0011584)

  • short tail(MP:0000592)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorSatoshi Yonezawa (Aichi Human Service Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data