Strain Information | |
---|---|
Image | ![]() |
BRC No. | RBRC02361 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | NOD.129S2(B6)-Pdcd1<tm1Hon> |
Former Common name | NOD-Pdcd1<-/-> mouse |
H-2 Haplotype | |
ES Cell line | D3 [129S2/SvPas] |
Background strain | NOD/ShiJcl |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. Wang J, Yoshida T, Nakaki F, Hiai H, Okazaki T, Honjo T Proc. Natl. Acad. Sci. USA, 102, 11823-11828 (2005). 16087865 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Pdcd1 MGI:104879 | programmed cell death 1 | 1 | Pdcd1<tm1Hon> MGI:2386184 | targeted mutation 1, Tasuku Honjo | |||
neo | neomycin resistance gene (E. coli) | 1 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | more 30 phenotypes |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse PD-1(immunoglobulin superfamily member) genomic DNA |
Research application | Diabetes and Obesity Research Immunology and Inflammation Research covid19_progression |
Specific Term and Conditions | 1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results. 2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Proc. Natl. Acad. Sci. USA, 102, 11823-11828 (2005). 3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE. |
Depositor | Tasuku Honjo (Kyoto University) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Jul 2012 |
BRC mice in Publications |
---|
No Data |