Strain Information | |
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Image | ![]() |
BRC No. | RBRC02365 |
Type | Transgene![]() |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Actb-Pdcd1)BHon |
Former Common name | PD-1-Tg (lineB) (C57BL/6), C57BL/6-Tg(ACTB-Pdcd1)B mouse |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Iwai Y, Terawaki S, Honjo T Int. Immunol., 17, 133-144 (2005). 15611321 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Pdcd1 MGI:104879 | programmed cell death 1 | UN | Pdcd1 | chicken beta-actin promoter |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | chicken β-actin promoter, mouse PD-1 cDNA, SV40 polyA |
Research application | Immunology and Inflammation Research |
Specific Term and Conditions | 1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results. 2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Int. Immunol., 17, 133-144 (2005). 3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE. |
Depositor | Tasuku Honjo (Kyoto University) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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No Data |