Strain Information | |
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Image | |
BRC No. | RBRC02369 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | B6;129-Rsph1<tm1Htan> |
Former Common name | |
H-2 Haplotype | |
ES Cell line | W9.5 [129S1/Sv-Oca2<+> Tyr<+> Kitl<+>] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Meichroacidin containing the membrane occupation and recognition nexus motif is essential for spermatozoa morphogenesis. Tokuhiro K, Hirose M, Miyagawa Y, Tsujimura A, Irie S, Isotani A, Okabe M, Toyama Y, Ito C, Toshimori K, Takeda K, Oshio S, Tainaka H, Tsuchida J, Okuyama A, Nishimune Y, Tanaka H J. Biol. Chem., 283(27):19039-19048(2008). 18453535 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Rsph1 MGI:1194909 | radial spoke head 1 homolog (Chlamydomonas) | 17 | Rsph1<tm1Htan> | targeted mutation 1, Hiromitsu Tanaka | |||
neo | neomycin resistance gene (E. coli) | 17 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 5 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | E. coli neo, mouse Rsph1(meichroacidin) genomic DNA |
Research application | Developmental Biology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Hiromitsu Tanaka (Osaka University) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Yin W, Livraghi-Butrico A, Sears PR, Rogers TD, Burns KA, Grubb BR, Ostrowski LE. Mice with a Deletion of Rsph1 Exhibit a Low Level of Mucociliary Clearance and Develop a Primary Ciliary Dyskinesia Phenotype. Am J Respir Cell Mol Biol 61(3) 312-321(2019) 30896965 |