Strain Information | |
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Image | |
BRC No. | RBRC02382 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6J-Tg(CXCL14)20 |
Former Common name | hBRAKlongExp20L, C57BL/6J-Tg(CXCL14)1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6J |
Appearance | |
Strain development | Developed by Ryu-Ichiro Hata, Kanagawa Dental College in 2007. |
Strain description | This transgenic mouse expresses the human chemokine (C-X-C motif) ligand 14 gene under he control of CAG promoter. line 20. Level of CXCL14/BRAK is 14 ng/ml plasma (in homozygote). |
Colony maintenance | |
References | Biochem. Biophys. Res. Commun., 348, 406-412 (2006). 16884687 Transgenic Res., 19, 1109-1117 (2010). 20333465 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter CXCL14chemokine (C-X-C motif) ligand 14UNCXCL14CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter poly ApolyAUNpoly A |
Ordering Information | |
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Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Human BRAKLong cDNA, SV40Late polyA |
Research application | |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. |
Depositor | Ryu-Ichiro Hata (Kanagawa Dental College) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Ishida Y, Kimura A, Nosaka M, Kuninaka Y, Hemmi H, Sasaki I, Kaisho T, Mukaida N, Kondo T. Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration. Sci Rep 7(1) 16833(2017) 29203799 |