Strain Data Sheet

RBRC02497

Strain Information

Image
BRC No.RBRC02497
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameHes7-cre#13
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Yumiko Saga, National Institute of Genetics in 2007. ICR mixed background.
Strain descriptionOct4/EGFP transgenic mice carry a cre-recombinase under control of Hes7 promoter/enhancer. Cre recombination efficiency is low.
Colony maintenance
References
The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.
Niwa Y, Masamizu Y, Liu T, Nakayama R, Deng C X, Kageyama R
Dev. Cell., 13, 298-304 (2007). 17681139

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Hes7 hairy and enhancer of split 7 (Drosophila)UNHes7
cre Phage P1 Cre recombinaseUNcre

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAcre-pA cDNA, Hes7 promoter-enhancer
    Research applicationCre/loxP system
    Developmental Biology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Cell., 13, 298-304 (2007).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorYumiko Saga (National Institute of Genetics)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)
    Saga Lab HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data