Strain Information | |
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Image | |
BRC No. | RBRC02605 |
Type | Transgene![]() |
Species | Mus musculus |
Strain name | B6.Cg-Tg(EF1A-GFP/Nrg1beta1*)TD1/BsiRbrc |
Former Common name | TD1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Miwako Ozaki, RIKEN Brain Science Institute in 2003. |
Strain description | Neuregulin-1 (NRG-1) is a neurotrophic factor that is known to regulate the development of various tissues and/or the life/death of cells through activation of the ErbB family receptor tyrosine kinases, and implicated as a potential susceptibility gene for schizophrenia. This stransgenic mice express a mutant NRG1beta1 (NRGB1) gene under the control of the EF1a-321 promoter. This strain is useful for investigating the function of the of NRG-1 gene. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
GFP | Green Fluorescent Protein (Aequorea victoria) | UN | |||||
Nrg1 MGI:96083 | neuregulin1-β | UN | Nrg1 |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | EF1a-321 promoter, mouse neuregulin1-β cDNA, Jellyfish GFP cDNA |
Research application | Fluorescent Proteins/lacZ System Neurobiology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from Dr. Miwako OZAKI (Fax: 03-5272-1208). The RECIPIENT must contact Dr. Miwako OZAKI and RIKEN BSI in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Miwako Ozaki (RIKEN) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |