Strain Data Sheet

RBRC02633

Strain Information

Image
BRC No.RBRC02633
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Bace2<tm1.2>
Former Common nameC57BL/6 BACE2 KO mice (BACE2Delta)
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strainC57BL/6JJmsSlc
Appearance
Strain developmentDeveloped by Shou Takashima and Yasuhiro Hashimoto, RIKEN Brain Science Institute in 2006.
Strain description
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJmsSlc] Homozygous mutant mice are viable and fertile.
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Bace2
MGI:1860440		beta-site APP-cleaving enzyme 216Bace2<tm1.2> targeted mutation 1.2, Yasuhiro Hashimoto
loxP phage P1 loxP16loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAPhage P1 loxP site, mouse Bace2 genomic DNA
    Research applicationCell Biology Research
    Cre/loxP system
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from use of the BIOLOGICAL RESOURCE. For period of two (2) years after deposition by the DEPOSITOR to the REKEN BRC, the RESIPIENT agrees to include the DEPOSITOR/DEVELOPER (Yashuhiro Hashimoto, Shou Takashima, Satoshi Futakawa) as a co-authors.
    DepositorYasuhiro Hashimoto (Fukushima Medical University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data