Strain Information | |
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Image | |
BRC No. | RBRC02717 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6J-Tg(CAG-xstopx-Plce1,-lacZ)ATkat |
Former Common name | CAG-flox-PLCε-A |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Overexpression of phospholipase Cepsilon in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T-cell infiltration. Takenaka N, Edamatsu H, Suzuki N, Saito H, Inoue Y, Oka M, Hu L, Kataoka T Eur J Immunol., 41(1):202-213(2011). 21182091 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
IRES | internal ribosomal entry site (EMCV) | UN | |||||
Plce1 | phospholipase C, epsilon 1 cDNA | UN | Plce1 | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) | |||
lacZ | beta-galactosidase (E. coli) | UN | |||||
loxP | phage P1 loxP | UN | loxP | ||||
loxP | phage P1 loxP | UN | loxP | ||||
poly A | SV40 polyA signal | UN | poly A |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 5 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Phage P1 loxP sites, STOP sequence contained a 550-bp C-terminal sequence of yeast His3 gene, mouse Plce1 cDNA, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), Simian virus 40 Large T antigen nuclear localization signal (NLS), E.coli lacZ, SV40 polyA signal |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. European Journal of Immunology, 41, 202-213 (2011).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Tohru Kataoka (Kobe University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |