Strain Data Sheet

RBRC03142

Strain Information

Image
BRC No.RBRC03142
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain namePcdhg-DgHS4-5
Former Common namedeltaHS4-5
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University in 2008. TT2 ES cells were used. The Pcdhg-DgHS4-5 allele was generated by crossing with Pcdhg-gHS4-5 mice (RBRC02811) and Sypc-cre mice.
Strain descriptionPcdhg knockout mice. The gHS4-5 genomic region of the Pcdhg gene was deleted.
Colony maintenanceHomozygote x Wild-type [C57BL/6J(Crlj)]
References
Identification of the cluster control region for the protocadherin-beta genes located beyond the protocadherin-gamma cluster.
Yokota S, Hirayama T, Hirano K, Kaneko R, Toyoda S, Kawamura Y, Hirabayashi M, Hirabayashi T, Yagi T
J Biol Chem. , 286, 31885-31895 (2011). 21771796

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pcdhg
MGI:3719124		protocadherin gamma cluster18Pcdhg<tm> targeted mutation
loxP phage P1 loxP18loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAMouse pcdh-g gene, phage P1 loxP
    Research applicationCre/loxP system
    Neurobiology Research
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR.
    DepositorTakeshi Yagi (Osaka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese)
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data