Strain Data Sheet

RBRC03166

Strain Information

Image
BRC No.RBRC03166
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6J.B6D2-Tg(CAG-Nmnat1)1Ara
Former Common nameNMNAT1-Tg
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearance
Strain developmentDeveloped by Naoki Yahata and Toshiyuki Araki, National Institute of Neuroscience in 2008.
Strain description
Colony maintenance
References
Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration.
Yahata N, Yuasa S, Araki T
J. Neurosci., 29, 6276-6284 (2009). 19439605

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Nmnat1
MGI:1913704		nicotinamide nucleotide adenylyltransferase 14Nmnat1 CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
  • Leber congenital amaurosis 9(MedGEN)

  • Leber congenital amaurosis(DisGeNET)

  • spondyloepiphyseal dysplasia, sensorineural hearing loss, impaired intellectual development, and leber congenital amaurosis(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • axon degeneration(MP:0005405)
    • Detailed phenotype data

    Ordering Information

    Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), mouse nicotinamide mononucleotide adenylyltransferase 1
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 29, 6276-6284 (2009). The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorToshiyuki Araki (National Center of Neurology and Psychiatry)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. CAGGS MTA (English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data