Strain Information | |
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Image | |
BRC No. | RBRC03653 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129-Arx<tm(Dp)Kki>/Rbrc |
Former Common name | Arx Dp-7 KI (B6), Arx (GCG)dup KI (B6) |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | Developed by Kunio Kitamura, Mitsubishi Kagaku Institute of Life Sciences. |
Strain description | |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | mouse Arx genomic DNA, E. coli neo, herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Research application | |
Specific Term and Conditions | The BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization. The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation. The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution. |
Depositor | Kunio Kitamura (Mitsubishi Kasei Institute of Life Sciences) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Lee K, Mattiske T, Kitamura K, Gecz J, Shoubridge C. Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation. Hum Mol Genet 23(4) 1084-94(2014) 24122442 |