Strain Information | |
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Image | |
BRC No. | RBRC03665 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | ICR;129(B6)-Arx<tm(GCG)Kki>/7-2Rbrc |
Former Common name | Arx (GCG)7-2 KI (ICR) |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | Developed by Kunio Kitamura, Mitsubishi Kagaku Institute of Life Sciences. CCE/EK.CCE ES cells were used to generate the mutant mice. |
Strain description | Arx GCG 7 repeats knock-in mice. 7 repeats of the GCG triple were inserted at the codon 330 of Arx gene. C57BL/6 mixed background (RBRC03654 and RBRC03656), 129 background (RBRC03655), C3H mixed background (RBRC03657), ICR mixed background (RBRC03665). |
Colony maintenance | Heterozygote x Wild-type [or Crlj:CD1(ICR)] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Arx MGI:1097716 | aristaless related homeobox | X | Arx<tm4Kki> MGI:4359177 | targeted mutation (GCG), Kunio Kitamura |
Phenotype | |
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Phenotype annotation from literatures by Mammalian phenotype ontology | more 19 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | ARX genomic DNA (mouse), Neomycin resistance gene (E. coli), MC1 promoter (HSV-tk由来)、PolyA signal (SV40) |
Research application | Mouse Models for Human Disease |
Specific Term and Conditions | The BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization. The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation. The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution. |
Depositor | Kunio Kitamura (Mitsubishi Kasei Institute of Life Sciences) |
Strain Status | ![]() |
Strain Availability | ![]() |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |