Strain Data Sheet

RBRC03797

Strain Information

Image
BRC No.RBRC03797
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S6-Egflam<tm1Tfir>
Former Common name129S6/SvEvTac-Egflam<tm1Tfir>
H-2 Haplotype
ES Cell lineTC1 [129S6/SvEvTac]
Background strain129S6/SvEvTac
Appearance
Strain development
Strain description
Colony maintenance
References
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.
Sato S, Omori Y, Katoh K, Kondo M, Kanagawa M, Miyata K, Funabiki K, Koyasu T, Kajimura N, Miyoshi T, Sawai H, Kobayashi K, Tani A, Toda T, Usukura J, Tano Y, Fujikado T, Furukawa T
Nat. Neurosci., 11, 923-931 (2008). 18641643

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Egflam
MGI:2146149		EGF-like, fibronectin type III and laminin G domains15Egflam<tm1Tfir>
MGI:3808156		targeted mutation 1, Takahisa Furukawa
neo neomycin resistance gene (E. coli)15 mouse phosphoglycerate kinase promoter (PGK promoter)
SV40 polyA signal15

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal cone electrophysiology(MP:0004022)

  • abnormal eye physiology(MP:0005253)

  • abnormal retina cone cell morphology(MP:0001006)

  • abnormal retina rod cell morphology(MP:0001005)

  • abnormal rod electrophysiology(MP:0004021)
    • Detailed phenotype data

    Ordering Information

    Donor DNAMouse PGK promoter, E.coli Neomycin resistance gene, SV40 PolyA signal, mouse Egflam genomic DNA
    Research applicationNeurobiology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Neurosci., 11, 923-931 (2008). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University).
    DepositorTakahisa Furukawa (Osaka Bioscience Institute)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityLive mouse (3 to 6 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data