Strain Data Sheet

RBRC03830

Strain Information

Image
BRC No.RBRC03830
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameSTOCK Tg(Pitx2 17k-lacZ)26Hmd
Former Common namePitx2 17-LacZ(26)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Hamada and Shiratori, Graduate School of Frontier Biosciences, Osaka University in 2001.
Strain description
Colony maintenance
References
Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.
Shiratori H, Sakuma R, Watanabe M, Hashiguchi H, Mochida K, Sakai Y, Nishino J, Saijoh Y, Whitman M, Hamada H
Mol. Cell., 7, 137-149 (2001). 11172719

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.
Shiratori H, Yashiro K, Shen M M, Hamada H
Development, 133, 3015-3025 (2006). 16835440

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
lacZ beta-galactosidase (E. coli)UN mouse Pitx2 promoter

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
    • Detailed phenotype data

    Ordering Information

    Donor DNAE. coli lacZ, mouse Pitx2 genomic DNA
    Research applicationFluorescent Proteins/lacZ System
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Cell., 7, 137-149 (2001). Development, 133, 3015-3025 (2006).
    DepositorHiroshi Hamada (RIKEN CDB)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data