Strain Data Sheet

RBRC03947

Strain Information

Image
BRC No.RBRC03947
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129B6-Apc<tm1(GFP)Yasu>
Former Common nameApc-IRES-GFP
H-2 Haplotype
ES Cell lineV6.5 [(C57BL/6J x 129S4/SvJae)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Apc
MGI:88039		APC, WNT signaling pathway regulator18Apc<tm1(GFP)Yasu>
MGI:6472931		targeted mutation 1, Yasuhiro Yamada
  • classic familial adenomatous polyposis(DisGeNET)

  • colorectal cancer(MedGEN)

  • colorectal carcinoma(DisGeNET)
    • more 5 Diseases
  • desmoid tumor(DisGeNET)

  • familial adenomatous polyposis 1(MedGEN)

  • gastric adenocarcinoma and proximal polyposis of the stomach(MedGEN)

  • gastric cancer(MedGEN)

  • hepatocellular carcinoma(MedGEN)
    • GFP Green Fluorescent Protein (Aequorea victoria)18
    Ires internal ribosomal entry site (EMCV)18

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNAEncephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), Jellyfish Gfp cDNA, mouse Apc genomic DNA
    Research applicationCancer Research
    Cell Biology Research
    Fluorescent Proteins/lacZ System
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers.
    DepositorYasuhiro Yamada (Gifu University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data