Strain Data Sheet

RBRC03983

Strain Information

Image
BRC No.RBRC03983
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129(FVB)-Atp6v0c<tm1.1Ywd>
Former Common nameV-ATPase c-subunit KO mouse; ATP6V0Cnull
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm.
Ge-Hong Sun-Wada, Hiroyuki Tabata, Yoh Wada
Sci. Rep., 11(1):19355 (2021). 34588579

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Atp6v0c
MGI:88116		ATPase, H+ transporting, lysosomal V0 subunit C17Atp6v0c<tm1.1Ywd>
MGI:6473167		targeted mutation 1.1, Yoh Wada
loxP phage P1 loxP17loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal fertility/fecundity(MP:0002161)

  • decreased fertilization frequency(MP:0009647)
    • Detailed phenotype data

    Ordering Information

    Donor DNAphage P1 loxP site, mouse Atp6v0c genomic DNA
    Research applicationCre/loxP system
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorYoh Wada (Osaka University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    Sun-Wada GH, Tabata H, Wada Y.
    Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm.
    Sci Rep 11(1) 19355(2021) 34588579