Strain Data Sheet

RBRC03985

Strain Information

Image
BRC No.RBRC03985
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.B6D2-Tg(Mt-Cd14)M14S
Former Common nameMCD14S
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearance
Strain developmentDeveloped by Yasunori Higuchi, Ohita Medical University in 1997.
Strain description
Colony maintenance
References
CD14 transgenic mice expressing membrane and soluble forms: comparisons of levels of cytokines and lethalities in response to lipopolysaccharide between transgenic and non-transgenic mice.
Tamura Y, Higuchi Y, Kataoka M, Akizuki S, Matsuura K, Yamamoto S
Int. Immunol., 11, 333-339 (1999). 10221645

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cd14 CD14 antigenUNCd14 mouse Mt promoter
SV40 polyA signalUN

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased circulating interleukin-6 level(MP:0008597)

  • decreased circulating tumor necrosis factor level(MP:0008554)
  • Detailed phenotype data

    Ordering Information

    Donor DNAMouse CD14, SV40 PolyA signal
    Research applicationCell Biology Research
    Immunology and Inflammation Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorYasunori Higuchi (Oita University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data