Strain Data Sheet

RBRC04186

Strain Information

Image
BRC No.RBRC04186
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.B6CB-Adam11<tm1Sag>
Former Common nameAdam11-KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strainC57BL/6NCrlCrlj
Appearance
Strain development
Strain description
Colony maintenance
References
Altered nociceptive response in ADAM11-deficient mice.
Takahashi E, Sagane K, Nagasu T, Kuromitsu J
Brain Res., 1097, 39-42 (2006). 16729981

Deficits in spatial learning and motor coordination in ADAM11-deficient mice.
Takahashi E, Sagane K, Oki T, Yamazaki K, Nagasu T, Kuromitsu J
BMC Neurosci., 7, 19 (2006). 16504143

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal spatial learning(MP:0001463)

  • impaired coordination(MP:0001405)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse Adam11 genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neomycin resistance gene
    Research application
    Specific Term and ConditionsRECIPIENT must make MTA specified by DEPOSITOR with DEPOSITOR prior to obtaining the BIOLOGICAL RESOURCE.
    DepositorKoji Sagane (Eisai Co., Ltd.)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data