Strain Data Sheet

RBRC04698

Strain Information

Image
BRC No.RBRC04698
TypeCongenic
SpeciesMus musculus
Strain nameA/J-7A<SM>
Former Common nameA.SM-Chr.7A
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Tamio Ohno, Nagoya University Graduate School of Medicine in 2010.
Strain descriptionHomozygous mice for SM allele are postnatal lethal (die within 1 hr after birth.
Colony maintenance
References
Neonatal lethality of mouse A/J-7SM consomic strain is caused by an insertion mutation in the Dchs1 gene.
Yuki Miyasaka, Takeshi Kobayashi, Naoya Gotoh, Masako Kuga, Misato Kobayashi, Fumihiko Horio, Katsunori Hashimoto, Tsutomu Kawabe, Tamio Ohno
Mamm. Genome, 34(1):32-43 (2023). 36434174

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Dchs1
MGI:2685011
dachsous cadherin related 17Dchs1
  • mitral valve prolapse, myxomatous 2(MedGEN)

  • van Maldergem syndrome 1(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • embryonic lethality, complete penetrance(MP:0011092)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorTamio Ohno (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    Miyasaka Y, Kobayashi T, Gotoh N, Kuga M, Kobayashi M, Horio F, Hashimoto K, Kawabe T, Ohno T.
    Neonatal lethality of mouse A/J-7SM consomic strain is caused by an insertion mutation in the Dchs1 gene.
    Mamm Genome 34(1) 32-43(2023) 36434174