Strain Data Sheet

RBRC04857

Strain Information

Image
BRC No.RBRC04857
TypeInbred
SpeciesMus musculus
Strain nameC57BL/10JMsHir
Former Common nameB10/Hir
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentMaintained by Tomohisa Hirobe, National Institute of Radiological Sciences. Introduced into National Institute of Radiological Sciences at 1986 from National Institute of Genetics. Deposited to RIKEN BRC at F139.
Strain descriptionC57BL/10 inbred mice strain. Black (a/a B/B C/C D/D P/P E/E). High number of melanocytes.
Colony maintenanceSibling x Sibling
References
Control of melanocyte proliferation and differentiation in the mouse epidermis.
Hirobe T
Pigment Cell Res., 5, 1-11 (1992). 1631016

Genetic and epigenetic control of the proliferation and differentiation of mouse epidermal melanocytes in culture.
Hirobe T, Abe H
Pigment Cell Res., 12, 147-163 (1992). 10385911

Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle.
Hirobe T
Histol Histopathol., 10, 223-237 (1995). 7756740

Role of keratinocyte-derived factors involved in regulating the proliferation and differentiation of mammalian epidermal melanocytes.
Hirobe T
Pigment Cell Res., 18, 2-12 (2005). 15649147

How are proliferation and differentiation of melanocytes regulated?
Hirobe T
Pigment Cell Melanoma Res., 24(3):462-478 (2011). 21375698

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Pigmnet Cell Melanoma Res., 24(3):462-478 (2011). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorTomohisa Hirobe (National Institute of Radiological Sciences (NIRS))
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    Hamanaka T, Nishizawa K, Sakasegawa Y, Oguma A, Teruya K, Kurahashi H, Hara H, Sakaguchi S, Doh-Ura K.
    Melanin or a Melanin-Like Substance Interacts with the N-Terminal Portion of Prion Protein and Inhibits Abnormal Prion Protein Formation in Prion-Infected Cells.
    J Virol 91(6) (2017) 28077650