Strain Data Sheet

RBRC05271

Strain Information

Image
BRC No.RBRC05271
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameICR-Tg(p16-luc)53Eiha/Rbrc
Former Common namep16-luc (Acc. No. CDB0416T-53)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Eiji Hara, The Cancer Institute, Japanese Foundation for Cancer Research.
Strain descriptionp16-luc transgenic mice. These mice have a human p16<lnk4a> gene locus tagged with firefly luciferase.
Colony maintenanceCarrier x Noncarrier [or Crossing to Crlj : CD1(ICR)]
References
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.
Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann D J, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E
J. Cell Biol., 186, 393-407 (2009). 19667129

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
luc luciferaseUNluc human CDKN2A promoter
neo neomycin resistance gene (E. coli)UN

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAHuman CDKN2A (p16ink4) genomic DNA, Firefly luciferase cDNA, E. coli neo
    Research application
    Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Eiji Hara, The Cancer Institute of Japanese Foundation for Cancer Research, E-mail:eiji.hara@jfcr.or.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0416T-53 and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Cell Biol. 2009 186(3):393-407.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
    DepositorRIKEN CDB (RIKEN CDB)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data