Strain Information | |
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Image | |
BRC No. | RBRC05432 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | C57BL/6N-D1Pas1<tm1(KOMP)Vlcg>/D4 |
Former Common name | B6-D1Pas1 KO#D4 |
H-2 Haplotype | |
ES Cell line | VGB6 [C57BL/6NTac] |
Background strain | C57BL/6NTac |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
D1Pas1 MGI:91842 | DNA segment, Chr 1, Pasteur Institute 1 | 1 | D1Pas1<tm1(KOMP)Vlcg> MGI:4399403 | targeted mutation 1, Velocigene | |||
lacZ | beta-galactosidase (E. coli) | 1 | |||||
loxP | phage P1 loxP | 1 | loxP | ||||
loxP | phage P1 loxP | 1 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 1 |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Velocigene cassette ZEN-Ub1(E. coli lacZ, SV40 polyA, Phage P1 loxP sites, human ubiquitin C promoter, synthetic bacterial EM7 promoter (T7 phage), E. coli neo, mouse Pgk1 polyA), mouse D1Pas1 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | |
Depositor | RIKEN BRC (RIKEN BRC) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Ogonuki N, Kyogoku H, Hino T, Osawa Y, Fujiwara Y, Inoue K, Kunieda T, Mizuno S, Tateno H, Sugiyama F, Kitajima TS, Ogura A. Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes. EMBO Rep 23(7) e54992(2022) 35587095 |
Inoue H, Ogonuki N, Hirose M, Hatanaka Y, Matoba S, Chuma S, Kobayashi K, Wakana S, Noguchi J, Inoue K, Tanemura K, Ogura A. Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells. Biochem Biophys Res Commun 478(2) 592-8(2016) 27473657 |