Strain Data Sheet

RBRC05449

Strain Information

Image
BRC No.RBRC05449
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6(129)-Tg(Plp1-tTS)1Kftnk
Former Common namePLP-tTS Tg, B6-PLP-tTS Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Kenji Tanaka, National Institute for Physiological Sciences. The transgene was injected into the pronuclei of C57BL/6J fertilized eggs. C57BL/6 and 129 mixed background.
Strain descriptionPLP-tTS transgenic mice. These transgenic mice express tetracycline-controlled transcriptional silencer (tTS) gene under the control of the mouse PLP promoter. tTS expression is detected in oligodendrocytes.
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
tTS E. coli Tetracycline repressor (tetR), human ZFP KRAB domain cDNAUNtTS

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse PLP promoter, tTS (E. coli Tetracycline repressor (tetR), human ZFP KRAB domain cDNA), SV40 polyA signal
    Research applicationTet system
    Specific Term and ConditionsThe availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. Prior to requesting the BIOLOGICAL RESOURCE, RECIPIENT must inform the DEPOSITOR of his project using the Approval Form. If the
    use of this BIOLOGICAL RESOURCE results in scientific publications, the RECIPIENT should cite Kenji F. Tanaka as co-author in the first paper.
    DepositorKenji Tanaka (Keio University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data