Strain Data Sheet

RBRC05532

Strain Information

Image
BRC No.RBRC05532
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC3H/HeN-Tg(Cd4-CD4)1Yiw
Former Common nameC3-Cd4-CD4 Tg#1
H-2 Haplotype
ES Cell line
Background strainC3H/HeNSlc
Appearance
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2011. The transgene was injected into the pronuclei of C3H/HeNSlc fertilized eggs. C3H background.
Strain descriptionTransgenic mice expressing human CD4 gene in T cells under the control of the mouse Cd4 promoter.
Colony maintenanceCarrier x Noncarrier [or Crossing to C3H/HeNSlc]
References
Nuclear import of the preintegration complex is blocked upon infection by human immunodeficiency virus type 1 in mouse cells.
Tsurutani N, Yasuda J, Yamamoto N, Choi B I, Kadoki M, Iwakura Y
J. Virol., 81(2):677-688 (2007). 17079325

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
CD4 (human) CD4 antigenUNCD4 (human) mouse Cd4 promoter

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
    • Detailed phenotype data

    Ordering Information

    Donor DNACd4 promoter (mouse), CD4 cDNA (human), rat beta globin intron sequence, SV40 polyA signal
    Research application
    Specific Term and ConditionsPlease obtain the written consent from Professor Yoichiro Iwakura(iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science)for the use.
    DepositorYoichiro Iwakura (The University of Tokyo)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data