Strain Information | |
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Image | |
BRC No. | RBRC05582 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Ikzf3<tm1(KOMP)Vlcg>/CB3 |
Former Common name | |
H-2 Haplotype | |
ES Cell line | VGB6 [C57BL/6NTac] |
Background strain | C57BL/6NTac |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP11loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP11loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11human ubiquitin C promoter |
Ordering Information | |
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Donor DNA | Velocigene cassette ZEN-Ub1(E. coli lacZ, pA, Phage P1 loxP sites, human ubiquitin C promoter, E. coli neo, pA), mouse Ikzf3 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | |
Depositor | RIKEN BRC (RIKEN BRC) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Read KA, Jones DM, Pokhrel S, Hales EDS, Varkey A, Tuazon JA, Eisele CD, Abdouni O, Saadey A, Leonard MR, Warren RT, Powell MD, Boss JM, Hemann EA, Yount JS, Xin G, Ghoneim HE, Lio CJ, Freud AG, Collins PL, Oestreich KJ. Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity. Nat Commun 14(1) 1652(2023) 36964178 |