Strain Information | |
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Image | |
BRC No. | RBRC05603 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.FVB-Tg(Col1a1-cre)1Kry |
Former Common name | alpha 1(I)-Cre, B6-Col1a1Cre Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Gerard Karsenty, Department of Molecular and Human Genetics, Baylor College of Medicine, Texas in 2002. The transgene was injected into the pronuclei of FVB fertilized eggs. The mice were crossed to C57BL/6J. |
Strain description | Col1a1-cre transgenic mice. These transgenic mice express cre recombinase under the control of the mouse collagen, type I, alpha 1 promoter. |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl] |
References | Dev. Dyn., 224, 245-251(2002). 12112477 |
Health Report | |
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Examination Date / Room / Rack | 2024/02/19Room:4-ARack:B 2023/11/20Room:4-ARack:B 2023/08/21Room:4-ARack:B 2023/06/26Room:4-ARack:B 2023/05/22Room:4-ARack:B 2023/02/20Room:4-ARack:B 2022/11/21Room:4-ARack:B 2022/08/22Room:4-ARack:B 2022/05/23Room:4-ARack:B |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinaseUNcretransgene insertion 1, Gerard Karsentymouse alpha 1(I)-collagen promoter |
Ordering Information | |
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Donor DNA | Mouse alpha 1 (I)-collagen promoter, Bacteriophage P1 Cre recombinase gene, Mouse Metallothionein MT-I polyA site |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Dyn., 224, 245-251 (2002). |
Depositor | Yasushi Okazaki (Saitama Medical University) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Hayata T, Chiga M, Ezura Y, Asashima M, Katabuchi H, Nishinakamura R, Noda M. Dullard deficiency causes hemorrhage in the adult ovarian follicles. Genes Cells 23(5) 345-356(2018) 29521016 Yoshioka H, Okita S, Nakano M, Minamizaki T, Nubukiyo A, Sotomaru Y, Bonnelye E, Kozai K, Tanimoto K, Aubin JE, Yoshiko Y. Single-Cell RNA-Sequencing Reveals the Breadth of Osteoblast Heterogeneity. JBMR Plus 5(6) e10496(2021) 34189385 |