Strain Information | |
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Image | |
BRC No. | RBRC05657 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | C57BL/6J-Tg(CAG-Cox8/DsRed2)1Rin |
Former Common name | mtDsRed2 Tg, B6-CAG-Cox8/DsRed2 Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Hiroshi Shitara, Akitsugu Sato and Hiromichi Yonekawa, Tokyo Metropolitan Institute of Medical Science. C57BL/6J background. |
Strain description | These transgenic mice express DsRed2 in mitochondria. This strain is useful for morphological analysis of mitochondria in vivo. |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl] |
References | Comprehensive application of an mtDsRed2-Tg mouse strain for mitochondrial imaging. Yamaguchi J, Nishiyama S, Shimanuki M, Ono T, Sato A, Nakada K, Hayashi J, Yonekawa H, Shitara H Transgenic Res., 21, 439-447 (2012). 21792696 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Cox8 | cytochrome c oxidase 8 | UN | Cox8 | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) | |||
DsRed2 | Red Fluorescent Protein (Discosoma sp.) | UN | DsRed2 | ||||
HA | human influenza virus HA (hemagglutinin) tag sequence | UN | HA |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), mouse cytochrome C oxidase subunit VIII (mitochondrial inner membrane electron transport chain) cDNA, human influenza virus HA (hemagglutinin) tag sequence, Discosoma sp. DsRed2 cDNA |
Research application | Cell Biology Research Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Transgenic Res., 21, 439-447 (2012). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit organization for a not-for-profit research. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Hiromichi Yonekawa (Tokyo Metropolitan Institute of Medical Science) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |