Strain Data Sheet

RBRC05707

Strain Information

Image
BRC No.RBRC05707
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Sec16b<tm1.1Hko>
Former Common nameSec16B delta lox/+ (GWAS001), B6-Sec16b KO
H-2 Haplotype
ES Cell lineM1 [(C57BL/6 x 129)F1]
Background strain
Appearance
Strain developmentDeveloped by Dr. Haruhiko Koseki, RIKEN Center for Allergy and Immunology. M1 ES cells derived from (C57BL/6 x 129)F1-Kitl<+> were used for the generation of knockout mice. Exon 4 and neo cassette were removed by crossing with CAG-Cre mice (C57BL/6 background). The mutant mice were crossed to C57BL/6J.
Strain descriptionSecB16 (Sec16b) gene knockout mice. Exon 4 was removed. Homozygous mice show no obvious abnormality.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Sec16b
MGI:2148802		SEC16 homolog B, endoplasmic reticulum export factor1Sec16b<tm1.1Hko> targeted mutation 1.1, Haruhiko Koseki
loxP phage P1 loxP1loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAP1 Phage loxP, Mouse Sec16b genomic DNA
    Research applicationCre/loxP system
    Specific Term and ConditionsThe RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorHaruhiko Koseki (RIKEN)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data