Strain Information | |
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Image | |
BRC No. | RBRC06013 |
Type | Transgene |
Species | Mus musculus |
Strain name | ICR-Tg(Hes1-luc2/Hes1)1Imayo |
Former Common name | Luc2-Hes1 fusion BAC ; Hes1-luc3/Hes1 Tg#1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Itaru Imayoshi and Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2011. The transgene was injected into the pronuclei of ICR fertilized eggs. |
Strain description | Hes1 BAC transgenic mice, in which Luc2-Hes1 fusion protein is expressed. |
Colony maintenance | Carrier x Noncarrier [or Crossing to Slc:ICR] |
References | Science, 342(6163):1203-8. doi: 10.1126/science.1242366. 24179156 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) siteUNFrt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HAhuman influenza virus HA (hemagglutinin) tag sequenceUNHA Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPUNloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter luc2Photinus pyralis LuciferaseUNluc2mouse Hes1 promoter |
Ordering Information | |
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Donor DNA | Photinus pyralis Optimized luciferase (synthetic), yeast Frt (flippase recombination target) site, human influenza virus HA (hemagglutinin) tag sequence, mouse Hes1 genomic DNA (BAC clone RP23-8N20), Phage P1 loxP site(derived from pBACe3.6 vector, BAC clone RP23-8N20) |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science DOI: 10.1126/science.1242366In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Itaru Imayoshi (E-mail: iimayosh@virus.kyoto-u.ac.jp) and Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). |
Depositor | Drs. Ryoichiro Kageyama and Itaru Imayoshi (Kyoto University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |