Strain Data Sheet
RBRC06086
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC06086 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6-Tg(Arc-EGFP/Arc)3Hbto |
| Former Common name | Arc-pro-GFP-Arc Tg mouse |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Hiroyuki Okuno and Haruhiko Bito, Graduate School of Medicine, The University of Tokyo in 2007. The transgene was injected into the pronuclei of C57BL/6NCrlSlc fertilized eggs. |
| Strain description | Arc-EGFP/Arc transgenic mice having a monomeric EGFP and mouse Arc cDNA fusion gene under the control of the Arc promoter. |
| Colony maintenance | Carrier x Noncarrier [C57BL/6NCrSlc] Tg mice are viable and fertile. |
| References | Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIbeta. Okuno H, Akashi K, Ishii Y, Yagishita-Kyo N, Suzuki K, Nonaka M, Kawashima T, Fujii H, Takemoto-Kimura S, Abe M, Natsume R, Chowdhury S, Sakimura K, Worley P F, Bito H Cell, 149, 886-898 (2012). 22579289 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Arc | activity regulated cytoskeletal-associated protein | UN | Arc | ||||
| EGFP | Enhanced Green Fluorescent Protein (Aequorea victoria) | UN | EGFP | ||||
| GH | Growth hormone polyA (Bovine) | UN | GH | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | mouse Arc promoter, jellyfish GFP cDNA, mouse Arc cDNA, Bovine Growth Hormone polyA signal[Bacteriophage SP6 promoter was not detected by PCR.] |
| Research application | Fluorescent Proteins/lacZ System |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 149, 886-898 (2012).Any use of the Material shall require written pre-approval by the Depositor. None of the provisions of this Agreement should provide for the transfer or licensing of any of the rights concerning the Material, such as ownership rights, copyrights, and the industrial property rights that belong to University of Tokyo or the Depositor. Any project carried out using the Material shall be considered in principle as a collaboration with the Depositor, unless otherwise agreed upon. In the event that new results are obtained from research and development by using the Material, the Recipient shall inform the Depositor immediately of the details of those results. Intellectual property rights arising out of the new results from research and development mentioned will be jointly owned by Depositor and the Recipient. The Depositor and the Recipient shall consult with each other with respect to their respective shares. If the Recipient intends to use the new results from research and development for the purpose of making profit, the Recipient shall immediately inform the Depositor of the details of its intended use and consult with the Depositor how to handle consideration and the like arising from the intended use. |
| Depositor | Haruhiko Bito (The University of Tokyo) |
| Strain Status |  Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Jul 2014 |
BRC mice in Publications |
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| No Data |