Strain Data Sheet

RBRC06192

Strain Information

Image
BRC No.RBRC06192
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Trib3<tm1Nah>
Former Common nameNudin1-KO, B6-Trib3 KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Naohiro Hashimoto, National Center for Geriatrics and Gerontology in 2004. The mutant mice were backcrossed to C57BL/6.
Strain descriptionNudin1 (Trib3) gene knockout mice. Homozygous mutant mice show no obvious abnormality.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
References
Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues.
Moriya-Sato A, Hida A, Inagawa-Ogashiwa M, Wada M R, Sugiyama K, Shimizu J, Yabuki T, Seyama Y, Hashimoto N
Biochem. Biophys. Res. Commun., 279, 62-68 (2000). 11112418

Expression of an acyl-CoA synthetase, lipidosin, in astrocytes of the murine brain and its up-regulation during remyelination following cuprizone-induced demyelination.
Song S Y, Kato C, Adachi E, Moriya-Sato A, Inagawa-Ogashiwa M, Umeda R, Hashimoto N
J. Neurosci. Res., 85(16):3586-97 (2007). 17722065

Health Report

Examination Date / Room / Rack2024/10/07Room:3-BRack:DSentinel mouse program
2024/07/08Room:3-BRack:DAdditional tests
2024/04/08Room:3-BRack:DSentinel mouse program
2024/01/09Room:3-BRack:DSentinel mouse program
2023/10/10Room:3-BRack:DSentinel mouse program
2023/07/10Room:3-BRack:DSentinel mouse program
2023/04/10Room:3-BRack:DSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Trib3
MGI:1345675		tribbles pseudokinase 32Trib3<tm1Nah> targeted mutation 1, Naohiro Hashimoto
neo neomycin resistance gene (Klebsiella pneumoniae)2 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), Klebsiella pneumoniae neomycin resistance gene, mouse Trib3 genomic DNA
    Research applicationDiabetes and Obesity Research
    covid19_progression
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorNaohiro Hashimoto (National Center for Geriatrics and Gerontology)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data