Strain Information | |
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Image | |
BRC No. | RBRC06298 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | CAnPt.Cg-Aicda<tm2.1Hon> |
Former Common name | BALBcAnPt Aicda G23S, BALBPt-AID/G23S KI |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Developed by Reiko Shinkura, Nagahama Institute of Bio-Science and Technology, and Tasuku Honjo, Graduate School of Medicine, Kyoto University. Bruce 4 ES cells were used. The mutant mice were backcrossed to BALB/cAJcl, and then to BALB/cAnPt over 5 times. |
Strain description | Aicda G53S mutant knock-in mice. BALB/cAnPt background. For the details, please contact the developer (Dr. Reiko Shinkura, Nagahama Institute of Bio-Science and Technology). |
Colony maintenance | Homozygote x Homozygote |
References | Nat. Immunol., 5, 707-712 (2004). 15195091 Nat. Immunol., 12, 264-270 (2011). 21258321 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP |
Ordering Information | |
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Donor DNA | Phage P1 loxP, mouse Aicda (G23S) genomic DNA |
Research application | Cre/loxP system Immunology and Inflammation Research |
Specific Term and Conditions | 1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results. 2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Nat. Immunol., 12, 264-270 (2011). 3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE. |
Depositor | Tasuku Honjo (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |