Strain Data Sheet

RBRC06509

Strain Information

Image
BRC No.RBRC06509
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameICR.Cg-Tg(Oct4dPE-creERT2)4
Former Common nameOct4dPE-CreERT2 Tg#4, ICR-Oct4dPE-CreER Tg#4
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Atsushi Suzuki, Faculty of Engineering, Yokohama National University in 2012. The transgene was injected into the pronuclei of B6C3F1 fertilized eggs. ICR mixed background.
Strain descriptionOct4 deltaPE-creER transgenic mice.
Colony maintenanceCarrier x Noncarrier [or Crossing to Jcl:MCH(ICR)]
References
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells.
Yeom Y I, Fuhrmann G, Ovitt C E, Brehm A, Ohbo K, Gross M, Hubner K, Scholer H R
Development., 122(3), 881-894 (1996). 8631266

Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice.
Yoshimizu T, Sugiyama N, De Felice M, Yeom Y I, Ohbo K, Masuko K, Obinata M, Abe K, Scholer H R, Matsui Y
Dev Growth Differ., 41(6), 675-684 (1999). 10646797

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
ERT2 estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A)UNERT2
cre Phage P1 Cre recombinaseUNcre mouse Oct3/4 deltaPE enhancer
SV40 polyAUN

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAMouse Oct3/4 deltaPE enhancer, phage P1 Cre recombinase, Human Estrogen receptor (ERT2), SV40 polyA
    Research applicationCre/loxP system
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorAtsushi Suzuki (Yokohama National University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Cre-ERT(2): NOTICE TO RECIPIENT
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data