Strain Information | |
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Image | |
BRC No. | RBRC06516 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Tdrd7<tm1.1Chum> |
Former Common name | T7 KO, B6-Tdrd7 KO |
H-2 Haplotype | |
ES Cell line | KY1.1[(C57BL/6J x 129S6/SvEvTac)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Shinichiro Chuma, Institute for Frontier Medical Sciences, Kyoto University in 2011. (C57BL/6J x 129S6/SvEvTac)F1 derived ES cells were used to generate the mutant mice. The mice were crossed to C57BL/6. |
Strain description | Trd7 gene knockout mice. Male homozygous mice are sterile, displaying small testis with abnormal spermatid morphology. Exons 8-12 were removed by cre excision. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Proc. Natl. Acad. Sci. USA, 28. 10579-10584 (2011). 21670278 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP4loxP |
Ordering Information | |
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Donor DNA | phage loxP site, mouse Tdrd7 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Shinichiro Chuma (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |