Strain Data Sheet

RBRC06568

Strain Information

Image
BRC No.RBRC06568
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameC3H/HeN-Pax3<Sp-Nag>
Former Common nameDws, C3-Dws
H-2 Haplotype
ES Cell line
Background strainC3H/HeNCrlCrlj
Appearance
Strain developmentDeveloped by Tamio Ohno, Nagoya University Graduate School of Medicine in 2014.
Strain descriptionDominant white spotting. Spontaneous mutation arose in C3H/HeN congenic strain. Details unknown.
Colony maintenanceHeterozygote x Wild-type [or Crossing to C3H/HeNCrlCrlj]
References
A new missense mutation in the paired domain of the mouse Pax3 gene.
Ohno T, Maegawa T, Katoh H, Miyasaka Y, Suzuki M, Kobayashi M, Horio F
Exp Anim, 66(3), 245-250 (2017). 28381738

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pax3
MGI:97487
paired box 31Pax3<Sp-Nag> splotch Nagoya
  • alveolar rhabdomyosarcoma(DisGeNET, MedGEN)

  • craniofacial-deafness-hand syndrome(MedGEN)

  • Waardenburg syndrome type 1(DisGeNET, MedGEN)
  • more 2 Diseases
  • Waardenburg syndrome type 3(MedGEN)

  • Waardenburg syndrome(DisGeNET)
  • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • white spotting (MP:0002938)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorTamio Ohno (Nagoya University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data