Strain Information | |
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Image | |
BRC No. | RBRC09341 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Il33<tm1Snak> |
Former Common name | IL-33(Acc.No.CDB0631K) |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | IL-33 is a crucial amplifier of innate rather than acquired immunity. Oboki K, Ohno T, Kajiwara N, Arae K, Morita H, Ishii A, Nambu A, Abe T, Kiyonari H, Matsumoto K, Sudo K, Okumura K, Saito H, Nakae S Proc. Natl. Acad. Sci. USA, 107(43):18581-6 (2010). 20937871 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
GFP | Green Fluorescent Protein (Aequorea victoria) | 19 | |||||
Il33 | interleukin 33 | 19 | Il33 | targeted mutation 1, Susumu Nakae | |||
loxP | phage P1 loxP | 19 | loxP | ||||
loxP | phage P1 loxP | 19 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 19 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 5 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neomycin resistance gene, jellyfish GFP cDNA, mouse Il33 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System Immunology and Inflammation Research |
Specific Term and Conditions | (1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0631K and Web Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested (Proc Natl Acad Sci U S A. 2010 107(43):18581-6.). (3) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |