Strain Data Sheet

RBRC09352

Strain Information

Image
BRC No.RBRC09352
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameRECK(Acc.No.CDB0488K)
Former Common nameRECK(Acc.No.CDB0488K)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice.
Chandana E P, Maeda Y, Ueda A, Kiyonari H, Oshima N, Yamamoto M, Kondo S, Oh J, Takahashi R, Yoshida Y, Kawashima S, Alexander D B, Kitayama H, Takahashi C, Tabata Y, Matsuzaki T, Noda M
BMC Dev. Biol., 10, 84 (2010). 20691046

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site4Frt
Reck
MGI:1855698		reversion-inducing-cysteine-rich protein with kazal motifs4Reck<tm1.1Noda> targeted mutation 1.1, Makoto Noda
loxP phage P1 loxP4loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal angiogenesis(MP:0000260)

  • abnormal apical ectodermal ridge morphology(MP:0001676)

  • abnormal basal lamina morphology(MP:0004273)

  • abnormal blood vessel morphology(MP:0001614)

  • abnormal digit morphology(MP:0002110)
    • more 11 phenotypes
  • abnormal forelimb morphology(MP:0000550)

  • abnormal limb bud morphology(MP:0005650)

  • abnormal limb morphology(MP:0002109)

  • abnormal vascular endothelial cell morphology(MP:0006055)

  • abnormal vitelline vascular remodeling(MP:0004076)

  • absent ulna(MP:0004360)

  • decreased embryo size(MP:0001698)

  • dilated vasculature(MP:0004938)

  • embryonic lethality during organogenesis, complete penetrance(MP:0011098)

  • hemorrhage(MP:0001914)

  • internal hemorrhage(MP:0001634)
    • Detailed phenotype data

    Ordering Information

    Donor DNAloxP, frt
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. BMC Dev Biol., 10:84 (2010).(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Makoto Noda (mnoda@virus.kyoto-u.ac.jp)) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB0488K) and Web Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (BMC Dev Biol., 10:84 (2010).) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
    DepositorRIKEN CDB (RIKEN CDB)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data