Strain Data Sheet

RBRC09463

Strain Information

Image
BRC No.RBRC09463
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6-Mettl20<em1.2Yshk>
Former Common nameMettl20 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Role of METTL20 in regulating β-oxidation and heat production in mice under fasting or ketogenic conditions.
Tadahiro Shimazu, Tamio Furuse, Shabeesh Balan, Ikuko Yamada, Shuzo Okuno, Hiroko Iwanari, Takehiro Suzuki, Takao Hamakubo, Naoshi Dohmae, Takeo Yoshikawa, Shigeharu Wakana, Yoichi Shinkai
Sci. Rep., 19;8(1):1179 (2018). 29352221

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mettl20
MGI:2443575		methyltransferase like 206Mettl20<em1.2Yshk> endonuclease-mediated mutation 1.2, Yoichi Shinkai

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • increased basal metabolism(MP:0008965)

  • increased fatty acid beta-oxidation(MP:0014173)

  • increased oxygen consumption(MP:0005289)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorYoichi Shinkai (RIKEN)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data