Strain Data Sheet

RBRC09473

Strain Information

Image
BRC No.RBRC09473
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(Nms-IRES-iCre)
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms.
Lee I T, Chang A S, Manandhar M, Shan Y, Fan J, Izumo M, Ikeda Y, Motoike T, Dixon S, Seinfeld J E, Takahashi J S, Yanagisawa M
Neuron., 4;85(5), 1086-1102 (2015). 25741729

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Ires internal ribosomal entry site (EMCV)UN mouse Nms promoter
iCre phage P1 codon improved Cre (iCre)UNiCre

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAEncephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), phage P1 Cre recombinase (iCre), mouse Nms genomic DNA(BAC clone RP23-101P2), Phage P1 loxP site (derived from pBACe3.6 vector, BAC clone RP23-101P2)
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neuron. 2015 Mar 4;85(5):1086-102. doi: 10.1016. DEPOSITOR limits the use of BIOLOGICAL RESOURCE to not-for-profit institutions. DEPOSITOR limits the use of the BIOLOGICAL RESOURCE to academic purposes. For-profit institutions and recipient who intend to use BIOLOGICAL RESOURCE for commercial research purposes shall acquire prior written consent from the DEPOSITOR. Recipient shall acquire prior written consent from the DEPOSITOR prior to filing an application for patent or intellectual property or their rights based on the results of research using the BIOLOGICAL RESOURCE.
DepositorMasashi Yanagisawa (University of Texas Southwestern Medical Center at Dallas)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data